Laser Speckle Perfusion Imaging Systems

Laser speckle is the random interference pattern produced when coherent light scatters from a medium that can be imaged onto a detector such as a camera. Motion from scattering particles, such as red blood cells in the vasculature, leads to spatial and temporal variations in the speckle pattern. The Laser Speckle Contrast Imaging (LSCI) technology, also known as the Laser Speckle Imaging (LSI), is an imaging modality based on the analysis of the blurring effect of the speckle pattern.  LSCI utilizes intrinsic tissue contrast from dynamic light scattering to offer a reliable technique for direct visualizing perfusion status in real-time, which is full-field rapid imaging with high spatiotemporal resolution, and also being able to provide quantitative analyses of perfusion data.